Screening of enzyme inhibitors from foodstuffs

　Acquired immunodeficiency syndrome (AIDS) of humans is caused by the infection of human immunodeficiency virus type 1 (HIV-1). AIDS is one of major infectious diseases, like malaria and tuberculosis.  Inhibitors of HIV-1 reverse transcriptase (HIV-1 RT) have been developed and used for the treatment of AIDS. We have been screening inhibitors of HIV-1 RT from foodstuffs and analyzing their inhibitory effects.

a) Tailoring Functions of an Enzyme Used for research and diagnosis
b) Screening of enzyme inhibitors from fuudstuffs
c) Control of Reaction by an Enzyme Used for Producing Food Materials
d) Basic Research Aimed at Designing Useful Enzymes